CATEGORY
Overview Resource

From Liquid Biopsy to Functional 3D Models

AcroCyte's R3CE® CTC Medium is specifically formulated to maintain the viability and heterogeneity of rare circulating tumor cells from blood samples. This system enables a seamless transition from liquid biopsy to functional 3D expansion, providing a standardized, scaffold-free environment for real-time monitoring.
Scientific Evidence: Breakthrough Efficiency & Clinical Fidelity



I. Rapid CTC Expansion and Purification


  • High-Yield Expansion from Patient Samples: Achieve robust 3D spheroid growth and expansion into the millions directly from patient blood samples.

  • Efficient Model Generation: Rapidly transform rare CTCs from diverse patient populations (e.g., SCLC, Pancreatic Cancer) into viable 3D models.

  • Scalable Throughput: The platform supports high-density expansion in a standardized 24-well format, streamlining the transition from clinical sampling to actionable data.

II. Preservation of Circulating Tumor Microenvironment (c-TME)


  • Physiological Fidelity: Our platform uniquely preserves the Circulating Tumor Microenvironment (c-TME), maintaining the complex biological signaling of the original tumor.

  • Direct Interaction Observation: Enables high-resolution observation of the interactions between  CTC spheroids and their native interactive immune cells (DAPI/EpCAM/CK/CD45).

  • Superior Enumeration Yield: Successfully enumerate high-density CTC populations, providing highly representative and actionable data for downstream molecular profiling and longitudinal analysis.

 

Key Features
High Sensitivity Preservation
Optimized to maximize the recovery and 3D spheroid formation of rare CTC populations.
Phenotypic Fidelity
Preserves the original molecular markers and heterogeneity of the patient's tumor.
Integrated Workflow
Fully compatible with R³CE® FDA-designated Class I plates for hydrogel-free 3D culture.
Applications
Real-time Drug Sensitivity Pro
Monitor treatment response through longitudinal blood sampling and 3D expansion.
Immuno-Oncology Studies
Explore interactions between expanded CTCs and immune cells in a native-like 3D architecture.
CTC-Derived Biobanking
Establish living biobanks from minimally invasive liquid biopsy samples for long-term oncology research.
Specification
R³CE® CTC Medium Specification
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